Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | MIF | P14174 | 2/20 | 0.69 |
| ▸ | ESRRG | P62508 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | GCGR | P47871 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17290220 | 0.88 | MIF (0.76) | LMNAMIFESRRGRAB9ANPC1 | |
| SCHEMBL13903557 | 0.88 | MIF (0.76) | LMNAMIFESRRGRAB9ANPC1 | |
| SCHEMBL4274744 | 0.83 | ESRRG (0.72) | LMNAESRRGRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4274738 | 0.83 | ESRRG (0.72) | LMNAESRRGRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15672276 | 0.80 | LMNA (0.82) | LMNAMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16182575 | 0.79 | LMNA (0.80) | LMNAMIFRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28471694 | 0.78 | ESRRG (1.00) | LMNAESRRGRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24278445 | 0.78 | ESRRG (0.60) | LMNAESRRGRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16224308 | 0.78 | ESRRG (0.60) | LMNAESRRGRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6163128 | 0.78 | SCN4A (0.68) | ESRRGRAB9ANPC1SMN1; SMN2GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |