Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283339 | 0.83 | KDM1A (0.76) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL19283337 | 0.83 | KDM1A (0.76) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL684894 | 0.82 | KDM1A (0.66) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL17067844 | 0.81 | MAPT (0.59) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL684222 | 0.80 | KDM1A (0.71) | RAB9ASMN1; SMN2NPC1HTTSIRT1 | |
| SCHEMBL22925057 | 0.80 | NPC1 (0.78) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL684783 | 0.80 | KDM1A (0.82) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL12443162 | 0.80 | NPC1 (0.74) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL8298504 | 0.79 | KMT2A (0.64) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL22925019 | 0.79 | MAPT (0.58) | RAB9ASMN1; SMN2NPC1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |