Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | RAB9A | P51151 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28484762 | 0.80 | RAB9A (0.74) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL1669543 | 0.80 | SIRT1 (0.72) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL1669542 | 0.80 | SIRT1 (0.72) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL22925048 | 0.80 | RAB9A (0.73) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL19283297 | 0.79 | ESRRG (0.72) | NPC1SMN1; SMN2RAB9AMAPTKMT2A | |
| SCHEMBL19283296 | 0.79 | ESRRG (0.72) | NPC1SMN1; SMN2RAB9AMAPTKMT2A | |
| SCHEMBL13475703 | 0.77 | RAB9A (0.74) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL28900918 | 0.77 | RAB9A (0.74) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL22139564 | 0.77 | KMT2A (0.59) | NPC1SMN1; SMN2RAB9ATDP1MAPT | |
| SCHEMBL22925052 | 0.76 | POLB (0.82) | NPC1SMN1; SMN2RAB9ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |