Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31288170 | 0.77 | HDAC6 (0.45) | TDP1CA1CA2HDAC6PIK3CD | |
| SCHEMBL14349185 | 0.75 | PIK3CG (0.44) | HPGDSNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23331493 | 0.74 | NPC1 (0.48) | HPGDSNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28733769 | 0.74 | TRPV4 (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL29621046 | 0.74 | TRPV4 (0.43) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL14376067 | 0.74 | PIK3CG (0.40) | HPGDSNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13680469 | 0.73 | NPC1 (0.42) | HPGDSNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL31288126 | 0.73 | PTPN1 (0.55) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL22925552 | 0.73 | — | — | |
| SCHEMBL16090371 | 0.72 | TSHR (0.59) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012018-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2021-01-28 | — | — | WO | disclosed |