Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.33 |
| ▸ | HTR3B | O95264 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927104 | 0.89 | LMNA (0.33) | LMNACYP2C9TDP1PREP | |
| SCHEMBL18943176 | 0.81 | TDP1 (0.46) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL18177041 | 0.81 | TDP1 (0.46) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL16076329 | 0.81 | TDP1 (0.46) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL8277176 | 0.81 | LMNA (0.43) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL18829248 | 0.81 | TDP1 (0.46) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL22926910 | 0.81 | LMNA (0.43) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL15430116 | 0.81 | TDP1 (0.46) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL19883625 | 0.81 | TDP1 (0.46) | LMNACYP2C9TDP1PREPHTR3E | |
| SCHEMBL13528915 | 0.81 | LMNA (0.43) | LMNACYP2C9TDP1PREPHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325921-B2 | Optically active crosslinked cyclic secondary amine derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-05-10 | — | — | US | disclosed |
| US-20210024547-A1 | OPTICALLY ACTIVE CROSSLINKED CYCLIC SECONDARY AMINE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024547-A1 | OPTICALLY ACTIVE CROSSLINKED CYCLIC SECONDARY AMINE DERIVATIVE | MLLT3, MEN1, MLLT1 | LMNA 693/4885CYP2C9 2631/4885TDP1 4130/4885 |
| US-11325921-B2 | Optically active crosslinked cyclic secondary amine derivative | MLLT3, MEN1, MLLT1 | LMNA 693/4885CYP2C9 2631/4885TDP1 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.