⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954053 | 0.72 | — | — | |
| SCHEMBL9491084 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6132677 | 0.70 | HTT (0.31) | — | |
| SCHEMBL21377285 | 0.70 | — | — | |
| SCHEMBL19523955 | 0.67 | — | — | |
| SCHEMBL9490210 | 0.67 | GAA (0.31) | — | |
| SCHEMBL9801300 | 0.67 | GRM5 (0.30) | — | |
| SCHEMBL13093675 | 0.67 | — | — | |
| SCHEMBL13221860 | 0.67 | — | — | |
| Bromide SCHEMBL31466612 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380101-B1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2021-01-27 | — | — | EP | disclosed |