Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550236 | 0.83 | KDM4E (0.30) | — | |
| SCHEMBL5369459 | 0.80 | — | — | |
| SCHEMBL16948094 | 0.79 | MAPK1 (0.33) | — | |
| SCHEMBL23555211 | 0.78 | TP53 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6133166 | 0.78 | — | — | |
| SCHEMBL19942224 | 0.77 | — | — | |
| SCHEMBL2744458 | 0.77 | GRM2 (0.31) | — | |
| SCHEMBL23254096 | 0.77 | — | — | |
| SCHEMBL21028208 | 0.77 | PIK3CD (0.31) | — | |
| SCHEMBL2744441 | 0.77 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227234-B1 | SILICOALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND | UOP LLC (US) | 2021-05-26 | — | — | EP | claimed |
| US-20180258058-A1 | ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS | UOP LLC (US) | 2018-09-13 | — | — | US | claimed |
| US-9815706-B2 | Zeolites using an organo-1-oxa-4-azoniumcyclohexane compound | UOP LLC (US) | 2017-11-14 | — | — | US | claimed |
| EP-3227266-A2 | ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS | UOP LLC (US) | 2017-10-11 | — | — | EP | claimed |
| US-9751772-B2 | Aluminophosphate molecular sieves using an organo-1-oxa-4-azoniumcyclohexane compound | UOP LLC (US) | 2017-09-05 | — | — | US | claimed |
| US-20170044120-A1 | ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS | UOP LLC (US) | 2017-02-16 | — | — | US | claimed |
| US-9522896-B2 | Organo-1-oxa-4-azonium cyclohexane compounds | UOP LLC (US) | 2016-12-20 | — | — | US | claimed |
| US-20160159760-A1 | ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS | UOP LLC | 2016-06-09 | — | — | US | claimed |
| US-20160159656-A1 | ALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND | UOP LLC | 2016-06-09 | — | — | US | claimed |
| US-20160159655-A1 | ZEOLITES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND | UOP LLC | 2016-06-09 | — | — | US | claimed |
| WO-2023183520-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | A2A PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-3227234-B1 | SILICOALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND | UOP LLC (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10654817-B2 | Organo-1-oxa-4-azonium cyclohexane compounds | UOP LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20160120850-A1 | THIAZOLES AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (US) | 2016-05-05 | — | — | US | disclosed |
| US-20150344423-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA | PHENEX PHARMACEUTICALS AG (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150322070-A1 | PIPERIDINE INHIBITORS OF JANUS KINASE 3 | AUSPEX PHARMACEUTICALS, INC. | 2015-11-12 | — | — | US | disclosed |
| US-20150175562-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | PHENEX PHARMACEUTICALS AG (DE) | 2015-06-25 | — | — | US | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160120850-A1 | THIAZOLES AS MODULATORS OF RORyt | RORC, RORB, RORA | GRM5 935/4885 |
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | MUSK, ERBB2, NTRK1 | GRM5 2403/4885 |
| US-20150322070-A1 | PIPERIDINE INHIBITORS OF JANUS KINASE 3 | JAK2, JAK3, PAK3 | GRM5 1451/4885 |
| US-10654817-B2 | Organo-1-oxa-4-azonium cyclohexane compounds | OXSR1, OXER1, OCIAD1 | GRM5 2435/4885 |
| US-20160159760-A1 | ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS | OXSR1, OXER1, OCIAD1 | GRM5 2435/4885 |
| US-20150175562-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | RORA, RORB, RORC | GRM5 222/4885 |
| US-20150344423-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA | RORA, RORB, RORC | GRM5 71/4885 |
| US-20180258058-A1 | ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS | OXSR1, OXER1, OCIAD1 | GRM5 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.