⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289424 | 0.90 | TRPM2 (0.73) | — | |
| SCHEMBL20711203 | 0.89 | TRPM2 (0.66) | — | |
| SCHEMBL2295419 | 0.89 | TRPM2 (0.69) | — | |
| SCHEMBL2294678 | 0.88 | TRPM2 (0.68) | — | |
| SCHEMBL2291921 | 0.88 | TRPM2 (0.91) | — | |
| SCHEMBL22133756 | 0.87 | TRPM2 (0.66) | — | |
| SCHEMBL2292709 | 0.84 | TRPM2 (0.78) | — | |
| SCHEMBL13773217 | 0.83 | TRPM2 (1.00) | — | |
| SCHEMBL2288469 | 0.83 | TRPM2 (1.00) | — | |
| SCHEMBL2288477 | 0.83 | TRPM2 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |