SCHEMBL22930710

SCHEMBL22930710

CC(C)(C)C1=CC(=CO)C=C(C(C)(C)C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 1/20 0.44
GPR35 Q9HC97 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
CES2 O00748 1/20 0.43
PKM P14618 1/20 0.43
HPGD P15428 1/20 0.43
CES1 P23141 1/20 0.43
MPI P34949 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MCL1 Q07820 1/20 0.42
POLB P06746 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15235937 0.81 ATM (0.46) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL8676354 0.79 ATM (0.45) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL8410304 0.77 ATM (0.44) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL14307454 0.77 ATM (0.44) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL86001 0.77 ATM (0.41) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL4456724 0.77 ATM (0.41) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL4468492 0.75 ATM (0.40) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL8144898 0.75 ATM (0.43) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL19730332 0.74 KMT2A (0.66) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL85970 0.74 ATM (0.49) ATMNPC1KMT2AGPR35ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10908162-B2 Methods related to volatile compounds in genitourinary cancers THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-02-02 US disclosed