SCHEMBL85970

SCHEMBL85970

COC=C1C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.49
NPC1 O15118 1/20 0.49
KMT2A Q03164 1/20 0.49
GPR35 Q9HC97 1/20 0.49
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
CES2 O00748 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
CES1 P23141 1/20 0.41
MPI P34949 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MCL1 Q07820 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.34
TYR P14679 1/20 0.31
POLB P06746 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85988 0.79 ATM (0.42) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL16104560 0.79 ATM (0.42) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL4468463 0.77 ATM (0.41) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL4456520 0.76 ATM (0.40) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL8676354 0.76 ATM (0.45) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL14307454 0.74 ATM (0.44) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL8410304 0.74 ATM (0.44) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL22930710 0.74 ATM (0.44) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL16104561 0.73 ATM (0.38) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL85767 0.73 ATM (0.44) ATMNPC1KMT2AGPR35ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319650-B2 Cleaning process of a vinyl aromatic compounds distillation unit and processes including such cleaning process TOTALENERGIES ONETECH (FR) 2025-06-03 US claimed
US-20250109083-A1 CLEANING PROCESS OF A VINYL AROMATIC COMPOUNDS DISTILLATION UNIT AND PROCESSES INCLUDING SUCH CLEANING PROCESS TOTALENERGIES ONETECH (FR) 2025-04-03 US claimed
EP-4482814-A1 CLEANING PROCESS OF A VINYL AROMATIC COMPOUNDS DISTILLATION UNIT AND PROCESSES INCLUDING SUCH CLEANING PROCESS TotalEnergies OneTech (FR) 2025-01-01 EP claimed
CN-118871411-A Process for cleaning a distillation unit of vinylaromatic compounds and process comprising such a cleaning process 道达尔能源一技术 2024-10-29 CN claimed
WO-2023161222-A1 CLEANING PROCESS OF A VINYL AROMATIC COMPOUNDS DISTILLATION UNIT AND PROCESSES INCLUDING SUCH CLEANING PROCESS TOTALENERGIES ONETECH (FR) 2023-08-31 WO claimed
EP-1894968-B1 Rubber mixture for treads of vehicle tyres CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2018-05-02 EP claimed
EP-2726451-B1 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS NALCO CO (US) 2017-03-22 EP claimed
US-9090526-B2 Synergistic combination for inhibiting polymerization of vinyl monomers NALCO COMPANY (US) 2015-07-28 US claimed
US-20120316369-A1 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS ECOLAB USA INC. 2012-12-13 US claimed
EP-2216335-A1 TETRIACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF Institute of Mataria Medica, Chinese Academy of Medical Sciences (CN) 2010-08-11 EP claimed
JP-7041470-A None JP disclosed
US-20260028467-A1 POLYMERIZATION INHIBITORS FOR HIGH TEMPERATURE ETHYLENE FRACTIONATION TRAINS BL TECHNOLOGIES INC (US) 2026-01-29 US disclosed
EP-4590651-A1 POLYMERIZATION INHIBITORS FOR HIGH TEMPERATURE ETHYLENE FRACTIONATION TRAINS BL Technologies, Inc. (US) 2025-07-30 EP disclosed
US-12319650-B2 Cleaning process of a vinyl aromatic compounds distillation unit and processes including such cleaning process TOTALENERGIES ONETECH (FR) 2025-06-03 US disclosed
US-20250109083-A1 CLEANING PROCESS OF A VINYL AROMATIC COMPOUNDS DISTILLATION UNIT AND PROCESSES INCLUDING SUCH CLEANING PROCESS TOTALENERGIES ONETECH (FR) 2025-04-03 US disclosed
US-20090114878-A1 PROCESS FOR STABILIZING OLEFINICALLY UNSATURATED MONOMERS EVONIK DEGUSSA GMBH (DE) 2009-05-07 US disclosed
EP-0626377-B1 Method for producing benzylidene derivatives SHIONOGI & CO (JP) 1999-07-28 EP disclosed
US-5463052-A Nonsteroidal antiinflammatory agents SHIONOGI & CO., LTD. (JP) 1995-10-31 US disclosed
JP-H0741470-A PRODUCTION OF BENZYLIDENE DERIVATIVE SHIONOGI & CO LTD 1995-02-10 JP disclosed
EP-0626377-A1 Method for producing benzylidene derivatives SHIONOGI & CO., LTD. (JP) 1994-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028467-A1 POLYMERIZATION INHIBITORS FOR HIGH TEMPERATURE ETHYLENE FRACTIONATION TRAINS ELL, ETFB, ETFA ATM 363/4885NPC1 4331/4885KMT2A 1866/4885
US-20120316369-A1 SYNERGISTIC COMBINATION FOR INHIIBITING POLYMERIZATION OF VINYL MONOMERS QDPR, SDHA, BLVRB ATM 4346/4885NPC1 4863/4885KMT2A 2400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.