SCHEMBL2293244

SCHEMBL2293244

O=C(O)c1cccc([N+](=O)[O-])c1Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 3/20 0.59
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
TSHR P16473 1/20 0.55
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 1/20 0.54
CASP7 P55210 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HCAR3 P49019 1/20 0.51
CTSV O60911 1/20 0.51
CTSL P07711 1/20 0.51
MAPT P10636 2/20 0.51
KDM4E B2RXH2 2/20 0.51
ASPH Q12797 1/20 0.51
KDM8 Q8N371 1/20 0.51
GAA P10253 1/20 0.50
CDK2 P24941 1/20 0.49
POLB P06746 1/20 0.49
HSP90AA1 P07900 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12086509 0.88 TSHR (0.50) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL2443092 0.88 TSHR (0.50) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL16737201 0.88 TSHR (0.50) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL16737117 0.88 MAPT (0.51) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL22720165 0.86 KDM4E (0.60) MEN1KMT2ATSHRALDH1A1MAPK1
SCHEMBL7232832 0.85 MEN1 (0.57) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL16862294 0.85 MAPT (0.56) MEN1KMT2ATSHRALDH1A1MAPK1
SCHEMBL16737172 0.85 POLB (0.67) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL16862346 0.85 KMT2A (0.56) CXCR2MEN1KMT2ATSHRALDH1A1
SCHEMBL10815162 0.85 CXCR2 (0.67) CXCR2MEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325210-B Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-10-11 CN claimed
CN-118325210-A Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-07-12 CN claimed
CN-104829544-B A kind of method for preparing the carboxylic acid of azophenlyene 1 上海泰禾国际贸易有限公司 2017-12-26 CN claimed
CN-104829544-A Preparation method for phenazine-1-carboxylic acid SHANGHAI CAC CHEMICAL CO LTD 2015-08-12 CN claimed
CN-103373967-A Synthetic method of shenqinmycin DALIAN JOIN KING BIO CHEMICAL TECHNOLOGY CO LTD 2013-10-30 CN claimed
CN-118325210-B Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-10-11 CN disclosed
CN-118325210-A Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-07-12 CN disclosed
CN-110551117-B Phenazine compound containing oxazole ring and application of phenazine compound as agricultural bactericide 南京农业大学 2022-09-27 CN disclosed
CN-110551117-A Phenazine compound containing oxazole ring and application of phenazine compound as agricultural bactericide UNIV NANJING AGRICULTURAL 2019-12-10 CN disclosed
CN-105418518-B A kind of azophenlyene carboxylic acid ester compound and application thereof 沈阳中化农药化工研发有限公司 2018-09-04 CN disclosed
US-9856225-B2 Substituted phenazines as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-01-02 US disclosed
US-9856225-B2 Substituted phenazines as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-01-02 US disclosed
US-20090226940-A1 NOVEL FLUORESCENT DYES AND USES THEREOF ITI SCOTLAND LIMITED (GB) 2009-09-10 US disclosed
US-20090226940-A1 NOVEL FLUORESCENT DYES AND USES THEREOF ITI SCOTLAND LIMITED (GB) 2009-09-10 US disclosed
EP-1940965-A2 NOVEL FLUORESCENT DYES AND USES THEREOF ITI Scotland Limited (GB) 2008-07-09 EP disclosed
US-20080103205-A1 Pesticidal compositions and methods of use VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2008-05-01 US disclosed
WO-2007050867-A2 PESTICIDAL COMPOSITIONS AND METHODS OF USE VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-05-03 WO disclosed
WO-2007049057-A2 NOVEL FLUORESCENT DYES AND USES THEREOF ITI SCOTLAND LIMITED (GB) 2007-05-03 WO disclosed
WO-2007049057-A2 NOVEL FLUORESCENT DYES AND USES THEREOF ITI SCOTLAND LIMITED (GB) 2007-05-03 WO disclosed
EP-0172744-A2 Phenazinecarboxamide compounds DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226940-A1 NOVEL FLUORESCENT DYES AND USES THEREOF ACR, ANXA5, GLB1 CXCR2 4421/4885MEN1 3393/4885KMT2A 4502/4885
US-20080103205-A1 Pesticidal compositions and methods of use SLC47A1, SLC22A8, SLC47A2 CXCR2 3235/4885MEN1 2040/4885KMT2A 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.