Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.57 |
| ▸ | CKS1B | P61024 | 2/20 | 0.53 |
| ▸ | SKP1 | P63208 | 2/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461584 | 0.82 | CKS1B (0.62) | KIF18ACKS1BSKP1SKP2PTPN11 | |
| SCHEMBL22932959 | 0.81 | KDM4E (0.56) | KDM4EPKMMEN1KMT2AGPR119 | |
| SCHEMBL461585 | 0.80 | CKS1B (0.60) | KIF18ACKS1BSKP1SKP2PTPN11 | |
| SCHEMBL29161592 | 0.79 | CKS1B (0.56) | KIF18ACKS1BSKP1SKP2PTPN11 | |
| SCHEMBL3275117 | 0.78 | CKS1B (0.65) | CKS1BSKP1SKP2PTPN11ACHE | |
| SCHEMBL18162540 | 0.78 | BPTF (0.49) | KIF18ACKS1BSKP1SKP2KDM4E | |
| SCHEMBL4295070 | 0.78 | CKS1B (0.61) | KIF18ACKS1BSKP1SKP2PTPN11 | |
| SCHEMBL4949224 | 0.78 | CKS1B (0.57) | KIF18ACKS1BSKP1SKP2PTPN11 | |
| SCHEMBL29664252 | 0.78 | CKS1B (0.57) | KIF18ACKS1BSKP1SKP2PTPN11 | |
| SCHEMBL4524210 | 0.78 | CKS1B (0.57) | KIF18ACKS1BSKP1SKP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018023-A1 | SMALL MOLECULE GLP-1 RECEPTOR MODULATOR | 济南泰达领创医药技术有限公司 | 2021-02-04 | — | — | WO | disclosed |