Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 19/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938319 | 0.84 | CD38 (0.69) | CD38 | |
| SCHEMBL22936261 | 0.84 | CD38 (0.69) | CD38 | |
| SCHEMBL22932659 | 0.81 | CD38 (0.45) | CD38JAK2JAK1JAK3 | |
| SCHEMBL22933540 | 0.78 | CD38 (0.73) | CD38 | |
| SCHEMBL22933148 | 0.78 | CD38 (0.51) | CD38 | |
| SCHEMBL29696388 | 0.77 | LRRK2 (0.42) | CD38JAK2 | |
| SCHEMBL31484481 | 0.70 | CD38 (0.85) | CD38 | |
| SCHEMBL22936349 | 0.70 | CD38 (0.85) | CD38 | |
| SCHEMBL22947044 | 0.70 | CD38 (0.85) | CD38 | |
| SCHEMBL31484538 | 0.70 | CD38 (0.85) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021986-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | RIBON THERAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |