Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293668 | 1.00 | KMT2A (0.61) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL29278729 | 0.89 | KMT2A (0.49) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL29278728 | 0.89 | KMT2A (0.49) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL11644993 | 0.87 | MEN1 (0.62) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL3586660 | 0.84 | TTR (0.55) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL7824974 | 0.84 | TTR (0.55) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL2059439 | 0.84 | TSHR (0.60) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL2100528 | 0.83 | HSD17B10 (0.55) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL27650064 | 0.81 | KMT2A (0.52) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL15332076 | 0.81 | ERN1 (0.50) | KMT2AALDH1A1MEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145007-A2 | NOVEL HERBICIDE RESISTANCE GENES | Dow AgroSciences LLC (US) | 2010-01-20 | — | — | EP | claimed |
| WO-2008141154-A2 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2008-11-20 | — | — | WO | claimed |
| EP-1947926-A2 | NOVEL HERBICIDE RESISTANCE GENES | Dow AgroSciences LLC (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2007053482-A2 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2007-05-10 | — | — | WO | claimed |
| US-11371055-B2 | Herbicide resistance genes | CORTEVA AGRISCIENCE LLC (US) | 2022-06-28 | — | — | US | disclosed |
| EP-3241430-B1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2020-08-26 | — | — | EP | disclosed |
| US-10167483-B2 | Herbicide resistance genes | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| EP-3241430-A1 | NOVEL HERBICIDE RESISTANCE GENES | Dow AgroSciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20170211087-A1 | NOVEL HERBICIDE RESISTANCE GENES | PIONEER HI-BRED INTERNATIONAL, INC. | 2017-07-27 | — | — | US | disclosed |
| EP-2484202-B1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| US-9624505-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2145007-B1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| EP-1947926-A2 | NOVEL HERBICIDE RESISTANCE GENES | Dow AgroSciences LLC (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007053482-A2 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2007-05-10 | — | — | WO | disclosed |
| CN-1020106-C | Process for pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 1993-03-17 | — | — | CN | disclosed |
| EP-0257378-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-03 | — | — | EP | disclosed |
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0257378-A1 | Pyrimidine derivatives, their preparation and medicaments containing these derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-02 | — | — | EP | disclosed |
| CN-87105758-A | Pyrimidine derivatives, their production and use | — | 1988-03-02 | — | — | CN | disclosed |