Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586660 | 1.00 | TTR (0.55) | TTRPDK1MEN1KMT2AHSPB1 | |
| SCHEMBL10535474 | 0.87 | KMT2A (0.60) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL12992431 | 0.86 | TTR (0.50) | TTRPDK1MEN1KMT2AHSPB1 | |
| SCHEMBL2059439 | 0.85 | TSHR (0.60) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9780791 | 0.84 | TSHR (0.62) | PDK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9780804 | 0.84 | TSHR (0.62) | PDK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16823541 | 0.84 | PDK1 (0.48) | TTRPDK1MEN1KMT2AALDH1A1 | |
| SCHEMBL16823536 | 0.84 | PDK1 (0.48) | TTRPDK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2293667 | 0.84 | KMT2A (0.61) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL2293668 | 0.84 | KMT2A (0.61) | MEN1KMT2AALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097918-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED-2-NITRO-FLUOROBENZENES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| US-4684371-A | Oxidation hair dyes comprising m-phenylenediamine derivatives as coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1987-08-04 | — | — | US | disclosed |
| EP-0039455-B1 | COUPLING COMPONENTS FOR OXIDATION HAIR DYES, THEIR PRODUCTION AND HAIR DYEING COMPOSITION CONTAINING THESE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-07-04 | — | — | EP | disclosed |
| EP-0039455-A1 | Coupling components for oxidation hair dyes, their production and hair dyeing composition containing these | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-11-11 | — | — | EP | disclosed |