Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672779 | 0.86 | EPHX1 (0.58) | EPHX1ALOX5TSHRPTGS1PTGS2 | |
| SCHEMBL28021768 | 0.84 | TSHR (0.40) | EPHX1NPC1RAB9AITGB1ITGA5 | |
| SCHEMBL15568884 | 0.84 | TBXAS1 (0.51) | NPC1RAB9AITGB1ITGA5ALOX5 | |
| SCHEMBL22593510 | 0.84 | EPHX1 (0.50) | EPHX1NPC1RAB9AALOX5TAAR1 | |
| SCHEMBL15134805 | 0.84 | NPC1 (0.45) | EPHX1NPC1RAB9AITGB1ITGA5 | |
| SCHEMBL23643109 | 0.84 | EPHX1 (0.50) | EPHX1ALOX5TAAR1SLC6A2ALDH1A1 | |
| SCHEMBL934530 | 0.84 | TAAR1 (0.59) | EPHX1TAAR1SLC6A2ESR1 | |
| SCHEMBL23643108 | 0.84 | EPHX1 (0.50) | EPHX1ALOX5TAAR1SLC6A2 | |
| SCHEMBL14032489 | 0.84 | TAAR1 (0.59) | EPHX1TAAR1SLC6A2ESR1 | |
| SCHEMBL12118748 | 0.84 | EPHX1 (0.50) | EPHX1NPC1RAB9AALOX5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021017790-A1 | ALPHA-SYNUCLEIN AGGREGATION INDUCED LUMINESCENCE SYSTEM AND CONSTRUCTION AND USE THEREOF | 天津科技大学 | 2021-02-04 | — | — | WO | disclosed |