Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381322 | 1.00 | — | — | |
| SCHEMBL115596 | 0.94 | — | — | |
| SCHEMBL27995241 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTHRB | |
| Methylene Chloride SCHEMBL28119554 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRB | |
| SCHEMBL1447159 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53 | |
| SCHEMBL8117603 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53 | |
| SCHEMBL20357702 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53 | |
| SCHEMBL525705 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53 | |
| SCHEMBL1446511 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53 | |
| SCHEMBL20450717 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018018-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INIDBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2021-02-04 | — | — | WO | disclosed |
| CN-101309899-B | Fluorinated gemini surfactants | 3M INNOVATIVE PROPERTIES CO | 2012-07-18 | — | — | CN | disclosed |
| CN-101309899-A | Fluorinated gemini surfactants | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-19 | — | — | CN | disclosed |
| CN-101163731-A | Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers | DU PONT (US) | 2008-04-16 | — | — | CN | disclosed |
| CN-85102097-A | Process for preparing benzo-crown ethers | — | 1986-01-10 | — | — | CN | disclosed |