SCHEMBL22940644

SCHEMBL22940644

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)c3c5ccccc5ccc3c3nc5ccccn5c43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.39
RAB9A P51151 4/20 0.39
KDM4E B2RXH2 4/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
MAPK10 P53779 1/20 0.39
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GLA P06280 2/20 0.34
GAA P10253 2/20 0.34
PDE5A O76074 1/20 0.34
PDE10A Q9Y233 1/20 0.34
PARP1 P09874 1/20 0.33
AKT1 P31749 1/20 0.33
AKT2 P31751 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22940820 0.99 NPC1 (0.39) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22941585 0.97 KDM4E (0.37) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22940522 0.97 NPC1 (0.39) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22941340 0.97 NPC1 (0.39) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22940535 0.96 KDM4E (0.37) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22941337 0.95 RAB9A (0.36) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22940645 0.93 MEN1 (0.38) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22941338 0.93 KDM4E (0.36) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22941430 0.92 KDM4E (0.41) NPC1RAB9AKDM4EHSD17B10MEN1
SCHEMBL22941429 0.92 KDM4E (0.41) NPC1RAB9AKDM4EHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210036239-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-02-04 US disclosed