2-Amino-4-Nitrophenol

2-Amino-4-Nitrophenol

SCHEMBL22943

Nc1cc([N+](=O)[O-])ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 1.00
THRB P10828 1/20 1.00
ALDH1A1 P00352 6/20 0.62
TSHR P16473 3/20 0.62
GPR35 Q9HC97 3/20 0.62
MAPK1 P28482 2/20 0.62
TP53 P04637 1/20 0.62
HPGD P15428 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
CYP3A4 P08684 3/20 0.60
TDP1 Q9NUW8 6/20 0.59
ALOX15 P16050 3/20 0.59
ERN1 O75460 1/20 0.56
MAPT P10636 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
GFER P55789 1/20 0.54
KMT2A Q03164 1/20 0.54
ATM Q13315 1/20 0.54
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Amino-4-Nitrophenol SCHEMBL31297314 1.00 GAA (1.00) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL31193638 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL19950506 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL19950749 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL19950745 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL6894954 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL19950746 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL11137165 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL6894960 0.98 GAA (0.96) GAATHRBALDH1A1TSHRGPR35
2-Amino-4-Nitrophenol SCHEMBL10386089 0.96 GAA (0.92) GAATHRBALDH1A1TSHRGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7149 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117126138-B Compound for degrading target protein in ubiquitin-proteasome system, and preparation method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2026-05-22 CN claimed
EP-3723864-B1 THICKENED ONE-COMPONENT HAIR TONER HENKEL AG & CO KGAA (DE) 2026-01-14 EP claimed
EP-4633805-A1 PROCESS FOR PREPARING ALLYLIC ALCOHOL Firmenich SA (CH) 2025-10-22 EP claimed
US-12435227-B2 Marker inks and methods of preparing the marker inks Shenzhen Thousandshores Technology Co., Ltd. (CN) 2025-10-07 US claimed
US-20250282966-A1 MARKER INKS AND METHODS OF PREPARING THE MARKER INKS Shenzhen Thousandshores Technology Co., Ltd. (CN) 2025-09-11 US claimed
CN-119899114-A Preparation method of 2-amino-5-nitrophenol impurity 九江善水科技股份有限公司 2025-04-29 CN claimed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
WO-2025061335-A1 METHOD FOR DYEING KERATIN FIBRES, COMPRISING THE APPLICATION OF AN OXIDATIVE PRE-TREATMENT AGENT AND A DYE COMPRISING DIRECT DYES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
CN-119462404-A Preparation method of 2-amino-4-nitrophenol 河北瀛泓化工产品有限公司 2025-02-18 CN claimed
CN-116023280-B Synthesis method of 2-amino-4-nitrophenol 湖北丽康源化工有限公司 2024-12-13 CN claimed
US-4329503-A Process for the preparation of 2-amino-4-nitrophenol CASSELLA AKTIENGESELLSCHAFT (DE) 1982-05-11 US claimed
US-4321053-A Hair dyeing composition and process WELLA AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed
WO-1982000092-A1 HAIR COLORATION METHOD AND COMPOSITION THEREFOR KONRAD E 1982-01-21 WO claimed
EP-0043436-A1 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1982-01-13 EP claimed
EP-0037377-A1 Metal-complex dyestuffs, their preparation and use CIBA-GEIGY AG (CH) 1981-10-07 EP claimed
EP-0033099-A1 Process for the preparation of 2-amino-4-nitrophenol CASSELLA Aktiengesellschaft (DE) 1981-08-05 EP claimed
EP-0012965-A1 Product and process for dyeing hair Wella Aktiengesellschaft (DE) 1980-07-09 EP claimed
WO-1980001241-A1 COMPOSITION AND PROCESS FOR HAIR COLOURATION WELLA AG (DE) 1980-06-26 WO claimed
US-4100112-A Process for the production of amine silicate compounds and their resinous condensation products BLOUNT DAVID H 1978-07-11 US claimed
US-4082781-A SYNTHESIS OF 2-ALKANOYLAMINO-4-NITROPHENYL PHOSPHORYLCHOLINE-HYDROXIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1978-04-04 US claimed