Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Amino-4-Nitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.96 |
| ▸ | GAA | P10253 | 3/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Amino-4-Nitrophenol SCHEMBL22943 | 0.98 | GAA (1.00) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL31297314 | 0.98 | GAA (1.00) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL31193638 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950745 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950749 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950506 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL19950746 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL11137165 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL6894954 | 0.96 | GAA (0.96) | GAATHRBALDH1A1TSHRGPR35 | |
| 2-Amino-4-Nitrophenol SCHEMBL10386089 | 0.94 | GAA (0.92) | GAATHRBALDH1A1TSHRGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970581-A | The production technology of 2- Amino-4-nitrophenol | 石家庄阮蔻贸易有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109699848-A | The biological agent for treating Tilapia mossambica Streptococcus iniae disease | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109691587-A | Improve the phagostimulant processing method of Tilapia mossambica feed intake | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-04-30 | — | — | CN | claimed |
| CN-109497344-A | The feed for improving yield and its application in raising Tilapia mossambica | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109497345-A | The feed making method for preventing and treating Tilapia mossambica Streptococcus iniae disease | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-105733292-A | Preparation method of acid black ACE | 江苏盛吉化工有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-105566126-A | Method for preparing 2-amino-4-nitrophenol through liquid catalytic hydrogenation | SHENYANG RES INST CHEMICAL IND CO LTD | 2016-05-11 | — | — | CN | claimed |
| CN-107253914-B | The method for preparing 2- Amino-4-nitrophenol using Disperse Blue 2BLN byproduct | 青岛海湾集团有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-109970581-A | The production technology of 2- Amino-4-nitrophenol | 石家庄阮蔻贸易有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109699849-A | Improve the biological agent preparation process that Tilapia mossambica suffers from Streptococcus iniae disease cure rate | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109699848-A | The biological agent for treating Tilapia mossambica Streptococcus iniae disease | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109691588-A | Chinese medicine phagostimulant and its application in tilapia feed | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-109691587-A | Improve the phagostimulant processing method of Tilapia mossambica feed intake | 广西南宁市武鸣明山红农业科技开发有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-106866432-A | A kind of synthesis technique of nitrophenol and its intermediate | 九江善水科技股份有限公司 | 2017-06-20 | — | — | CN | disclosed |
| CN-105733292-A | Preparation method of acid black ACE | 江苏盛吉化工有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-105566126-A | Method for preparing 2-amino-4-nitrophenol through liquid catalytic hydrogenation | SHENYANG RES INST CHEMICAL IND CO LTD | 2016-05-11 | — | — | CN | disclosed |
| EP-1210299-B1 | METHOD OF PRODUCING HYDROXYL RADICALS FOR CHEMICAL REACTIONS | UNIV ABERTAY DUNDEE (GB) | 2004-03-10 | — | — | EP | disclosed |
| US-6692632-B1 | GENERATING MANGANESE IONS THROUGH ELECTROCHEMICAL DISSOLUTION OF METAL ELECTRODE EXPOSED TO ULTRASONIC ENERGY IN ELECTROLYTE; EXPOSURE TO HYDROGEN PEROXIDE TO GENERATE HYDROXYL RADICALS | UNIVERSITY OF ABERTAY DUNDEE (GB) | 2004-02-17 | — | — | US | disclosed |
| EP-1210299-A2 | METHOD OF PRODUCING HYDROXYL RADICALS FOR CHEMICAL REACTIONS | University of Abertay Dundee (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001016031-A2 | METHOD OF PRODUCING HYDROXYL RADICALS FOR CHEMICAL REACTIONS | UNIVERSITY OF ABERTAY DUNDEE (GB) | 2001-03-08 | — | — | WO | disclosed |