Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944214 | 0.88 | CHEK1 (0.57) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22944207 | 0.86 | CHEK1 (0.55) | CHEK1CHEK2 | |
| SCHEMBL22943204 | 0.83 | CHEK1 (0.67) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22943241 | 0.83 | CHEK1 (0.54) | CHEK1CHEK2KCNH2 | |
| SCHEMBL620384 | 0.83 | CHEK1 (0.61) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22944589 | 0.81 | CHEK1 (0.60) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22943185 | 0.76 | CHEK1 (0.69) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22944210 | 0.76 | CHEK1 (0.55) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22943186 | 0.75 | CHEK1 (0.68) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22943443 | 0.75 | CHEK1 (0.67) | CHEK1CHEK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021019514-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2021-02-04 | — | — | WO | disclosed |