Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944207 | 0.88 | CHEK1 (0.55) | CHEK1CHEK2 | |
| SCHEMBL22944214 | 0.87 | CHEK1 (0.57) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22943220 | 0.77 | CHEK1 (0.68) | CHEK1CHEK2 | |
| SCHEMBL22943209 | 0.76 | CHEK1 (0.65) | CHEK1CHEK2 | |
| SCHEMBL22944206 | 0.76 | CHEK1 (0.56) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22944582 | 0.75 | CHEK1 (0.64) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22944600 | 0.75 | CHEK1 (0.64) | CHEK1CHEK2 | |
| SCHEMBL22943424 | 0.75 | CHEK1 (0.64) | CHEK1CHEK2 | |
| SCHEMBL22943232 | 0.75 | CHEK1 (0.61) | CHEK1CHEK2 | |
| SCHEMBL22943190 | 0.74 | CHEK1 (0.62) | CHEK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021019514-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2021-02-04 | — | — | WO | disclosed |