SCHEMBL22944448

SCHEMBL22944448

CCC1CNC(C)CN1CC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.38
XIAP P98170 3/20 0.33
BIRC2 Q13490 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14104187 0.81 SIGMAR1 (0.38) SIGMAR1XIAPBIRC2
SCHEMBL22944469 0.81 SIGMAR1 (0.35) SIGMAR1
SCHEMBL13770623 0.78 SIGMAR1 (0.47) SIGMAR1
SCHEMBL6376833 0.78 SIGMAR1 (0.47) SIGMAR1
SCHEMBL3106152 0.78 SIGMAR1 (0.47) SIGMAR1
SCHEMBL26060560 0.78 SIGMAR1 (0.47) SIGMAR1
SCHEMBL13733316 0.78 XIAP (0.43) SIGMAR1XIAPBIRC2
SCHEMBL1191024 0.77 SIGMAR1 (0.33) SIGMAR1
SCHEMBL27387361 0.77 SIGMAR1 (0.33) SIGMAR1
SCHEMBL23040022 0.75 SIGMAR1 (0.52) SIGMAR1XIAPBIRC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021020586-A1 HETEROCYCLIC COMPOUND ファイメクス株式会社 2021-02-04 WO disclosed