Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17662686 | 0.93 | SLC6A4 (0.31) | SLC6A4SLC6A3 | |
| SCHEMBL22944895 | 0.81 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17662599 | 0.80 | EPHX1 (0.31) | — | |
| SCHEMBL202959 | 0.80 | USP2 (0.31) | LMNA | |
| SCHEMBL487371 | 0.80 | USP2 (0.31) | LMNA | |
| SCHEMBL20170950 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL25819859 | 0.78 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL487300 | 0.77 | — | — | |
| SCHEMBL13849274 | 0.77 | — | — | |
| SCHEMBL8015433 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021979-A2 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |