Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.44 |
| ▸ | KDM1A | O60341 | 6/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672346 | 0.82 | HDAC6 (0.51) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL22944355 | 0.82 | HDAC6 (0.51) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL29795160 | 0.79 | HDAC6 (0.47) | HDAC6KDM1AHDAC8HDAC1HDAC3 | |
| SCHEMBL22944075 | 0.74 | HDAC6 (0.54) | HDAC6KDM1AHDAC8HDAC4HDAC7 | |
| SCHEMBL29795226 | 0.74 | HDAC6 (0.48) | HDAC6KDM1AHDAC8HDAC4HDAC7 | |
| SCHEMBL22943788 | 0.74 | HDAC6 (0.48) | HDAC6KDM1AHDAC8HDAC4HDAC7 | |
| SCHEMBL22944079 | 0.72 | HDAC6 (0.54) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL29795216 | 0.72 | HDAC6 (0.54) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL22943785 | 0.72 | HDAC6 (0.54) | HDAC6HDAC8HDAC4HDAC7HDAC11 | |
| SCHEMBL22944082 | 0.71 | HDAC6 (0.55) | HDAC6KDM1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021979-A2 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |