Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12676791 | 0.84 | MMP2 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL22944442 | 0.78 | MMP2 (0.54) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL22924352 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL22924061 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL21583727 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL23020214 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL22924059 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL22924338 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL21283340 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL172724 | 0.73 | CA12 (0.45) | CA12CA1CA2MMP2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021020586-A1 | HETEROCYCLIC COMPOUND | ファイメクス株式会社 | 2021-02-04 | — | — | WO | disclosed |