Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 15/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22886096 | 0.89 | CAPN1 (0.51) | CAPN1 | |
| SCHEMBL20028068 | 0.87 | CAPN1 (0.48) | CAPN1 | |
| SCHEMBL20027848 | 0.84 | CAPN1 (0.46) | CAPN1 | |
| SCHEMBL20028431 | 0.84 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL21854063 | 0.84 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL20028398 | 0.81 | CAPN1 (0.45) | CAPN1 | |
| SCHEMBL21854216 | 0.79 | CAPN1 (0.52) | CAPN1 | |
| SCHEMBL22886539 | 0.79 | ALDH1A1 (0.42) | CAPN1 | |
| SCHEMBL20027849 | 0.79 | CAPN1 (0.48) | CAPN1 | |
| SCHEMBL22896350 | 0.79 | CAPN1 (0.46) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021816-A1 | CALPAIN INHIBITORS AND USES THEREOF FOR TREATING NEUROLOGICAL DISORDERS | BLADE THERAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |