Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22945858 | 0.94 | KMT2A (0.33) | L3MBTL1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL22945856 | 0.92 | TSHR (0.32) | L3MBTL1TDP1MEN1KMT2AMAPT | |
| SCHEMBL22946173 | 0.88 | SMN1; SMN2 (0.31) | HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL22946175 | 0.87 | ABCB1 (0.35) | L3MBTL1LMNAMAPK1TDP1ADORA2A | |
| SCHEMBL22945895 | 0.87 | MEN1 (0.35) | HCRTR1HCRTR2LMNAMEN1KMT2A | |
| SCHEMBL22946320 | 0.87 | MEN1 (0.34) | HCRTR1HCRTR2L3MBTL1LMNAMEN1 | |
| SCHEMBL23061289 | 0.84 | CNR1 (0.33) | L3MBTL1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL23061290 | 0.82 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL23061288 | 0.82 | ABCB1 (0.31) | — | |
| SCHEMBL22945896 | 0.81 | CNR1 (0.31) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018135-A1 | HETEROCYCLYL ALKYL SUBSTITUTED DICHLOROBENZOYL COMPOUNDS AND APPLICATIONS THEREOF | 东莞市东阳光农药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |