Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22945896 | 0.95 | CNR1 (0.31) | PKM | |
| SCHEMBL22945890 | 0.93 | HSD11B1 (0.31) | KMT2A | |
| SCHEMBL22946173 | 0.90 | SMN1; SMN2 (0.31) | SMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL22945860 | 0.87 | HCRTR1 (0.33) | MEN1KMT2ALMNASMN1; SMN2HCRTR1 | |
| SCHEMBL22946320 | 0.86 | MEN1 (0.34) | MEN1KMT2ALMNAGAASMN1; SMN2 | |
| SCHEMBL22945894 | 0.83 | ABCB1 (0.38) | MEN1KMT2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL22946181 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL30423372 | 0.83 | MAPT (0.37) | KMT2ALMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22946152 | 0.83 | MAPT (0.37) | KMT2ALMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22945858 | 0.81 | KMT2A (0.33) | MEN1KMT2ALMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018135-A1 | HETEROCYCLYL ALKYL SUBSTITUTED DICHLOROBENZOYL COMPOUNDS AND APPLICATIONS THEREOF | 东莞市东阳光农药研发有限公司 | 2021-02-04 | — | — | WO | disclosed |