Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aldrin SCHEMBL18376 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Aldrin SCHEMBL5933946 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Aldrin SCHEMBL119263 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Aldrin SCHEMBL5933947 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Aldrin SCHEMBL19032672 | 0.87 | CYP3A4 (0.76) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Aldrin SCHEMBL15538695 | 0.86 | CYP3A4 (0.77) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Endrin SCHEMBL8707183 | 0.84 | CYP3A4 (0.77) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Endrin SCHEMBL10671688 | 0.84 | CYP3A4 (0.77) | CYP3A4MAPTTSHRMAPK1LMNA | |
| Aldrin SCHEMBL10670456 | 0.83 | CYP3A4 (0.69) | CYP3A4MAPTTSHRMAPK1LMNA | |
| SCHEMBL11476909 | 0.81 | CYP3A4 (0.67) | CYP3A4MAPTTSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210033618-A1 | BIOLOGICAL STATUS CLASSIFICATION | RANDOX LABORATORIES LTD (GB) | 2021-02-04 | — | — | US | disclosed |