SCHEMBL22947724

SCHEMBL22947724

Clc1cccnc1-c1ccccc1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.54
DPP4 P27487 1/20 0.49
PTPRC P08575 2/20 0.46
CTSL P07711 1/20 0.46
CTSS P25774 1/20 0.46
PTPN13 Q12923 1/20 0.46
PTGS1 P23219 2/20 0.45
PTGS2 P35354 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
S100A4 P26447 1/20 0.43
CDC25B P30305 1/20 0.43
KCNA5 P22460 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.41
RORB Q92753 1/20 0.41
TDP2 O95551 1/20 0.41
NSD2 O96028 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31538678 1.00 CYP2A6 (0.54) CYP2A6DPP4PTPRCCTSLCTSS
SCHEMBL23636188 0.85 CYP2A6 (0.59) CYP2A6DPP4PTPRCCTSLCTSS
SCHEMBL20821396 0.84 DPP4 (0.65) CYP2A6DPP4PTPRCCTSLCTSS
SCHEMBL2975854 0.84 CNR2 (0.46) CYP2A6DPP4PTGS1PTGS2ALDH1A1
SCHEMBL31223211 0.82 CNR2 (0.45) CYP2A6DPP4PTGS1PTGS2ALDH1A1
SCHEMBL12854077 0.80 PTPRC (0.53) PTPRCCTSLCTSSPTPN13PTGS1
SCHEMBL12854065 0.79 PTPRC (0.55) CYP2A6PTPRCCTSLCTSSPTPN13
SCHEMBL12854121 0.79 PTPRC (0.57) PTPRCCTSLCTSSPTPN13PTGS1
SCHEMBL12854073 0.79 PTPRC (0.55) CYP2A6PTPRCCTSLCTSSPTPN13
SCHEMBL7647031 0.79 PTGS2 (0.58) CYP2A6PTPRCCTSLCTSSPTPN13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096528-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2022-02-25 CN disclosed
WO-2021020285-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2021-02-04 WO disclosed