Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.66 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | ODC1 | P11926 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260469 | 1.00 | HSD17B1 (1.00) | HSD17B1PTPN1MGAMODC1 | |
| SCHEMBL23483682 | 1.00 | HSD17B1 (1.00) | HSD17B1PTPN1MGAMODC1 | |
| SCHEMBL31237827 | 0.84 | PTPN1 (0.73) | HSD17B1PTPN1 | |
| Erybreadin B SCHEMBL29571677 | 0.80 | PTPN1 (1.00) | HSD17B1PTPN1MGAM | |
| Erybreadin B SCHEMBL31237953 | 0.80 | PTPN1 (1.00) | HSD17B1PTPN1MGAM | |
| SCHEMBL30645543 | 0.80 | HSD17B1 (0.66) | HSD17B1PTPN1 | |
| SCHEMBL27724151 | 0.80 | HSD17B1 (0.66) | HSD17B1PTPN1 | |
| SCHEMBL29377397 | 0.79 | PTPN1 (1.00) | HSD17B1PTPN1 | |
| SCHEMBL29384928 | 0.77 | HSD17B1 (0.62) | HSD17B1PTPN1MGAMODC1 | |
| SCHEMBL20960789 | 0.76 | HSD17B1 (0.61) | HSD17B1PTPN1MGAMODC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022111-A2 | β-ARRESTIN-MODULATING COMPOUNDS AND METHODS OF USING SAME | DUKE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |