Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18088401 | 0.82 | P2RX7 (0.75) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL19666011 | 0.79 | HDAC6 (0.79) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL19666012 | 0.79 | HDAC6 (0.79) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL18085887 | 0.78 | P2RX7 (0.74) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL19678427 | 0.77 | HDAC6 (1.00) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL16653780 | 0.77 | HDAC6 (1.00) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL16653782 | 0.77 | HDAC6 (1.00) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL19666006 | 0.77 | HDAC6 (1.00) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL19666090 | 0.77 | HDAC6 (1.00) | P2RX7HDAC6HDAC5HDAC4HDAC3 | |
| SCHEMBL16653771 | 0.76 | HDAC6 (0.78) | P2RX7HDAC6HDAC5HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210030899-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030899-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | HDAC1, HDAC11, HDAC3 | P2RX7 4700/4885HDAC6 13/4885HDAC5 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.