Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22301097 | 0.88 | KMT2A (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL25101955 | 0.87 | MEN1 (0.40) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL22872802 | 0.87 | NAMPT (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589671 | 0.87 | NAMPT (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589714 | 0.87 | NAMPT (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589907 | 0.87 | NAMPT (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589692 | 0.87 | NAMPT (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589715 | 0.87 | NAMPT (0.39) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589690 | 0.86 | DNM1 (0.42) | KMT2AMEN1CASP2EPHX1NAMPT | |
| SCHEMBL23589722 | 0.84 | NAMPT (0.37) | KMT2AMEN1CASP2EPHX1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022163-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-02-04 | — | — | WO | disclosed |