Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.49 |
| ▸ | WIZ | O95785 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30942516 | 1.00 | CRBN (0.53) | CRBNESR1IKZF2WIZCSNK1A1 | |
| SCHEMBL27302044 | 1.00 | CRBN (0.53) | CRBNESR1IKZF2WIZCSNK1A1 | |
| SCHEMBL27314019 | 0.95 | CRBN (0.57) | CRBNESR1IKZF2WIZ | |
| SCHEMBL24675672 | 0.95 | CRBN (0.52) | CRBNESR1IKZF2WIZ | |
| Hydrochloric Acid SCHEMBL27225872 | 0.94 | CRBN (0.51) | CRBNESR1IKZF2WIZ | |
| SCHEMBL22291560 | 0.93 | CRBN (0.53) | CRBNESR1 | |
| SCHEMBL22291663 | 0.93 | CRBN (0.53) | CRBNESR1IKZF2WIZ | |
| SCHEMBL22600233 | 0.91 | CRBN (0.60) | CRBNESR1IKZF2WIZ | |
| SCHEMBL24735305 | 0.91 | CRBN (0.60) | CRBNESR1IKZF2WIZ | |
| SCHEMBL29841272 | 0.91 | CRBN (0.60) | CRBNESR1IKZF2WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022163-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-02-04 | — | — | WO | disclosed |