SCHEMBL22952471

SCHEMBL22952471

C/C=C/C=C/C/C(C)=N\C(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.35
CNR1 P21554 2/20 0.35
PPARG P37231 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21241232 0.76 CNR2 (0.31) CNR2CNR1PPARGPPARDPPARA
SCHEMBL21232972 0.74 CNR2 (0.30) CNR2CNR1PPARGPPARDPPARA
SCHEMBL22955127 0.71 CNR1 (0.33) CNR2CNR1
SCHEMBL22952481 0.68 CNR1 (0.32) CNR2CNR1
SCHEMBL27304901 0.67 CNR2 (0.34) CNR2CNR1PPARGPPARDPPARA
SCHEMBL14346025 0.67 CNR2 (0.31) CNR2CNR1PPARGPPARDPPARA
SCHEMBL10262569 0.66
SCHEMBL17787398 0.64 CNR2 (0.38) CNR2CNR1PPARGPPARDPPARA
SCHEMBL22158322 0.63 LMNA (0.31)
SCHEMBL22158324 0.63 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210032222-A1 FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032222-A1 FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUNDS AND DERIVATIVES, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND APPLICATIONS THEREOF CBR3, CBR1, CYP8B1 CNR2 265/4885CNR1 203/4885PPARG 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.