Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | G6PD | P11413 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FGB | P02675 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952976 | 0.85 | HTR2A (0.33) | DRD1KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL22952972 | 0.83 | DRD1 (0.34) | DRD1DRD5SLC6A4HRH3DRD2 | |
| SCHEMBL22952980 | 0.83 | SLC6A4 (0.32) | SLC6A4HRH3 | |
| SCHEMBL22953389 | 0.79 | HTR2A (0.34) | DRD1DRD5HTR2APARP1 | |
| SCHEMBL22952971 | 0.76 | HTR2A (0.35) | DRD1KDM4EMAPTHPGDRECQL | |
| SCHEMBL22953344 | 0.73 | PARP1 (0.39) | DRD1DRD5CYP3A4HSD17B10MAPK1 | |
| SCHEMBL6345215 | 0.72 | HTR2A (0.46) | DRD1DRD5KDM4EMAPTHPGD | |
| SCHEMBL29383649 | 0.72 | HTR2A (0.46) | DRD1DRD5KDM4EMAPTHPGD | |
| Bromide SCHEMBL3668719 | 0.71 | HTR2A (0.45) | DRD1KDM4EMAPTHPGDRECQL | |
| SCHEMBL22952973 | 0.70 | PARP1 (0.38) | KDM4EMAPTHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |