Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953006 | 0.81 | HTR2C (0.36) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952931 | 0.77 | DRD1 (0.60) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953000 | 0.75 | ADRA2A (0.49) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952998 | 0.72 | ADRA2A (0.46) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953347 | 0.70 | ADRA2A (0.44) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953348 | 0.70 | ADRA2A (0.44) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953349 | 0.70 | ADRA2A (0.44) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953352 | 0.70 | ADRA2A (0.44) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22952995 | 0.69 | DRD1 (0.43) | ADRA2ADRD2ADRA2BADRA2CDRD1 | |
| SCHEMBL22953351 | 0.69 | ADRA2A (0.42) | ADRA2ADRD2ADRA2BADRA2CDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |