Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301409 | 0.89 | CYP2C9 (0.45) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2297836 | 0.88 | CYP3A4 (0.55) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9952934 | 0.80 | CYP2C9 (0.46) | MEN1KMT2APRNPCYP3A4CYP2C9 | |
| SCHEMBL14697404 | 0.79 | ALOX5 (0.49) | MEN1KMT2APRNPMAPTALOX5 | |
| SCHEMBL2300561 | 0.78 | CYP3A4 (0.69) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2297368 | 0.78 | ALOX5 (0.48) | MEN1KMT2APRNPCYP3A4CYP2C9 | |
| SCHEMBL18095501 | 0.78 | CYP2C9 (0.44) | MEN1KMT2APRNPCYP3A4CYP2C9 | |
| SCHEMBL14697648 | 0.77 | ALOX5 (0.45) | MEN1KMT2APRNPCYP3A4CYP2C9 | |
| Alcohol SCHEMBL9954178 | 0.77 | ALOX5 (0.48) | MEN1KMT2APRNPCYP3A4CYP2C9 | |
| SCHEMBL6119862 | 0.77 | MAPT (0.43) | MEN1KMT2APRNPCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103063-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-08-25 | — | — | WO | disclosed |