SCHEMBL2295390

SCHEMBL2295390

C=CC(=O)OCC1OC1C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.44
HPGD P15428 1/20 0.42
ALDH1A1 P00352 4/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
THRB P10828 2/20 0.36
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267873 0.88 ALDH1A1 (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11766531 0.83 HCAR2 (0.39)
SCHEMBL11766525 0.83 HCAR2 (0.39)
SCHEMBL28205413 0.81 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28454885 0.81 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28211848 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28218100 0.79 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7871538 0.79 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17839037 0.78 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17839031 0.76 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220227954-A1 POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE OAKTREE FUND ADMINISTRATION, LLC 2022-07-21 US claimed
CN-110511665-B Gloss oil for UV printing 广东希贵光固化材料有限公司 2021-08-17 CN claimed
EP-3862384-A2 POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE SiO2 Medical Products, Inc. (US) 2021-08-11 EP claimed
CN-112241107-A Positive photosensitive resin composition, photosensitive resin film, and display device using same 株式会社东进世美肯 2021-01-19 CN claimed
US-7189341-B2 Transition metal catalyst, an electroconductive material such as graphite; and a polymer binder blend of high molecular weight and low molecular weight acrylic (co)polymers, one having a higher glass transition temperature (Tg); catalytic inks for screen printing; use to make electrochemical sensors ANIMAS TECHNOLOGIES, LLC (US) 2007-03-13 US claimed
US-4332694-A IMMOBILIZATION OF ENZYMES CESKOSLOVENSKA AKADEMIE VED (CS) 1982-06-01 US claimed
US-20250263579-A1 CURE-ON-DEMAND POLYMERS AND METHODS OF MAKING AND USE THEREOF UNIV LOUISIANA STATE (US) 2025-08-21 US disclosed
US-20250145784-A1 POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES AND METHODS OF PLASMA TREATMENT SIO2 MEDICAL PRODUCTS INC (US) 2025-05-08 US disclosed
CN-116635487-B Acrylate resins, powder coating compositions containing them and powder coated substrates 阿克佐 诺贝尔国际涂料股份有限公司 2025-01-28 CN disclosed
US-12195603-B2 Polymeric surface having reduced biomolecule adhesion to thermoplastic articles and methods of plasma treatment SIO2 MEDICAL PRODUCTS, LLC (US) 2025-01-14 US disclosed
EP-4366685-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE PHYSICAL PROPERTIES OF HEALTHY AND DAMAGED HAIR Kevin Murphy Group Pty. Ltd. (AU) 2024-05-15 EP disclosed
CN-117651740-A Polyphenylene sulfide composite resin containing high filler content and molded article using the same 韩国商东丽先端素材股份有限公司 2024-03-05 CN disclosed
CN-116635487-A Acrylate resins, powder coating compositions containing them and powder coated substrates 阿克佐 诺贝尔国际涂料股份有限公司 2023-08-22 CN disclosed
US-5330686-A Crosslinked acrylic ester polymer, benzoxazine compound PPG INDUSTRIES, INC. (US) 1994-07-19 US disclosed
WO-1994004952-A1 TEMPERATURE STABLE AND SUNLIGHT PROTECTED PHOTOCHROMIC ARTICLES PPG INDUSTRIES, INC. (US) 1994-03-03 WO disclosed
US-5283360-A Opening epoxide ring with acidic reagent ATOCHEM (FR) 1994-02-01 US disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0183213-B1 THERMOSETTING PREFORM HAVING SUPERIOR TRANSPARENCY AND PROCESS FOR PRODUCING MOLDED ARTICLES FROM SAID PREFORM MITSUBISHI RAYON CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0108420-B1 IMAGE-TRANSMITTING SYNTHETIC RESIN ROD AND PROCESS FOR PRODUCING THE SAME MITSUBISHI RAYON CO., LTD. (JP) 1989-04-12 EP disclosed
US-4332694-A IMMOBILIZATION OF ENZYMES CESKOSLOVENSKA AKADEMIE VED (CS) 1982-06-01 US disclosed