Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23970489 | 0.97 | HDAC3 (0.31) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19661736 | 0.90 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL24001248 | 0.90 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL22954839 | 0.87 | EPHX2 (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20325417 | 0.84 | EPHX2 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19599927 | 0.82 | CES2 (0.34) | — | |
| SCHEMBL20305542 | 0.81 | STING1 (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19599855 | 0.81 | CES2 (0.37) | — | |
| SCHEMBL21634211 | 0.80 | STING1 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20325479 | 0.80 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266206-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2021018118-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1 PROTEINS | JANSSEN PHARMACEUTICA NV (BE) | 2021-02-04 | — | — | WO | disclosed |