SCHEMBL22955971

SCHEMBL22955971

c1ccc(-c2cc(-c3cccc(-c4c5ccccc5c(-c5cccc(-c6cncc7ccccc67)c5)c5ccccc45)c3)c(-c3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.50
CYP11B1 P15538 10/20 0.46
CYP11B2 P19099 10/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2B6 P20813 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
ERN1 O75460 3/20 0.41
ERBB2 P04626 2/20 0.40
CDK1 P06493 2/20 0.40
KDR P35968 1/20 0.40
NTSR1 P30989 1/20 0.39
CYP17A1 P05093 1/20 0.39
PRMT5 O14744 1/20 0.39
WDR77 Q9BQA1 1/20 0.39
MMP1 P03956 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22955979 0.94 PRKCZ (0.51) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL22955414 0.89 PRKCZ (0.50) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL21266819 0.89 PRKCZ (0.53) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL25113048 0.86 PRKCZ (0.38) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL22955623 0.84 PRKCZ (0.51) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL29850049 0.83 HPGD (0.39)
SCHEMBL21240013 0.83 HPGD (0.39)
SCHEMBL15497568 0.82 PRKCZ (0.55) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL24662633 0.82 PRKCZ (0.47) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9
SCHEMBL17320800 0.82 PRKCZ (0.48) PRKCZCYP11B1CYP11B2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210036230-A1 Organic Material for an Electronic Optoelectronic Device and Electronic Device Comprising the Organic Material NOVALED GMBH (DE) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036230-A1 Organic Material for an Electronic Optoelectronic Device and Electronic Device Comprising the Organic Material OCIAD1, OCIAD2, OR10J3 PRKCZ 4748/4885CYP11B1 1513/4885CYP11B2 1178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.