Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.41 |
| ▸ | ITGAL | P20701 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20661666 | 0.87 | ITGB2 (0.41) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL20840787 | 0.82 | HRH3 (0.43) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL21848380 | 0.81 | HRH3 (0.41) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL19483446 | 0.77 | CYP3A4 (0.47) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL19483449 | 0.77 | CYP3A4 (0.47) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL18159671 | 0.77 | ITGB2 (0.42) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL18159672 | 0.77 | ITGB2 (0.42) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL12319926 | 0.74 | HRH3 (0.42) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL12322755 | 0.72 | HRH3 (0.43) | HRH3HRH4ALDH1A1CYP1A2MEN1 | |
| SCHEMBL23787378 | 0.72 | ITGB2 (0.56) | HRH3HRH4ALDH1A1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913948-B2 | RNA interference in dermal and fibrotic indications | PHIO PHARMACEUTICALS CORP. (US) | 2021-02-09 | — | — | US | disclosed |