Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.57 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292923 | 0.88 | ADORA3 (0.71) | ADORA3ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2288205 | 0.86 | RXFP1 (0.60) | RXFP1ADORA2ACA1CA2CA4 | |
| SCHEMBL1798087 | 0.85 | RXFP1 (0.61) | RXFP1CA1CA2CA9PI4KA | |
| SCHEMBL2292121 | 0.84 | RXFP1 (0.57) | RXFP1ADORA2ACA1CA2CA4 | |
| SCHEMBL2293369 | 0.84 | RXFP1 (0.66) | RXFP1ADORA3CA1CA2CA4 | |
| SCHEMBL12379249 | 0.80 | RXFP1 (0.86) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2292456 | 0.80 | RXFP1 (0.86) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18297502 | 0.79 | NAE1 (0.54) | RXFP1CA2PI4KAPI4K2BPI4K2A | |
| SCHEMBL13773254 | 0.78 | RXFP1 (0.64) | RXFP1ADORA2ACA1CA2CA4 | |
| SCHEMBL19938137 | 0.77 | RXFP1 (0.59) | RXFP1CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | RXFP1 141/4885ADORA3 1669/4885ADORA2A 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.