SCHEMBL22959453

SCHEMBL22959453

C=C(NC(C)C)C(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
LMNA P02545 2/20 0.43
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
HSD17B10 Q99714 2/20 0.39
ADRA2C P18825 2/20 0.39
CTSD P07339 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA1A P35348 1/20 0.39
RGS12 O14924 1/20 0.39
GLA P06280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22803653 0.83 HSD17B10 (0.39) ALDH1A1LMNAHSD17B10ADRA2CCHRM2
SCHEMBL8118811 0.76 HDAC1 (0.56) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL24757742 0.75 HDAC3 (0.61) ALDH1A1LMNAHDAC3HDAC4HDAC1
SCHEMBL25668354 0.71 CYP3A4 (0.49) CYP3A4TSHRMEN1KMT2A
SCHEMBL9806266 0.70 HPGD (0.48) ALDH1A1LMNAHDAC3HDAC4HDAC1
SCHEMBL12197839 0.70 NPSR1 (0.45) ALDH1A1LMNAHSD17B10ADRA2CCHRM2
SCHEMBL22959429 0.69 SLC6A2 (0.48) ALDH1A1LMNAHSD17B10CYP3A4CYP2C19
SCHEMBL8697335 0.69 TDP1 (0.48) LMNAHDAC3HDAC4HDAC1HDAC7
SCHEMBL22959426 0.68 CNR1 (0.56) ALDH1A1LMNAHDAC3HDAC4HDAC1
SCHEMBL10710110 0.68 HSD17B10 (0.52) ALDH1A1LMNAHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021022932-A1 α-SUBSTITUTED PHENYL STRUCTURE-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND DISINFECTANT 郑州大学 2021-02-11 WO disclosed