Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108299 | 0.88 | ACP3 (0.48) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL4206682 | 0.78 | CTSD (0.46) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL9806266 | 0.78 | HPGD (0.48) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL2524121 | 0.78 | L3MBTL1 (0.44) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL16062547 | 0.76 | L3MBTL1 (0.54) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL17600356 | 0.75 | TDP1 (0.52) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL4525849 | 0.74 | LMNA (0.56) | L3MBTL1CYP2D6SRCHPGDDPP4 | |
| SCHEMBL8118811 | 0.74 | HDAC1 (0.56) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL585336 | 0.74 | CTSD (0.54) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL17599982 | 0.72 | TDP1 (0.45) | TDP1L3MBTL1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1997048674-A1 | DIARYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |