SCHEMBL229602

SCHEMBL229602

C#CCOc1ccc(CC(N)C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 1/20 0.59
▸ ITGA2B P08514 1/20 0.59
▸ SLC7A5 Q01650 3/20 0.54
▸ PTPN1 P18031 3/20 0.54
▸ PTGS1 P23219 3/20 0.53
▸ ALPI P09923 1/20 0.53
▸ PKM P14618 1/20 0.53
▸ XIAP P98170 1/20 0.53
▸ PPARA Q07869 1/20 0.48
▸ TPH1 P17752 2/20 0.47
▸ GRB2 P62993 1/20 0.47
▸ ALOX15 P16050 3/20 0.46
▸ HIF1A Q16665 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA4 P22748 1/20 0.46
▸ CA7 P43166 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229603 1.00 ITGB3 (0.59) ITGB3ITGA2BSLC7A5PTPN1PTGS1
Hydrochloric Acid SCHEMBL230409 0.98 ITGB3 (0.58) ITGB3ITGA2BSLC7A5PTPN1PTGS1
Hydrochloric Acid SCHEMBL230410 0.98 ITGB3 (0.58) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL29141465 0.94 ITGB3 (0.54) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL10001633 0.89 CA12 (0.47) ITGB3ITGA2BSLC7A5PTPN1PPARA
SCHEMBL4865204 0.88 CA12 (0.46) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL2802898 0.88 CA12 (0.46) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL28539110 0.88 SLC1A1 (0.58) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL28539108 0.88 SLC1A1 (0.58) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL231156 0.87 CA12 (0.45) ITGB3ITGA2BSLC7A5PTPN1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2422 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577575-B2 Methods and compositions for promoting non-natural amino acid-containing protein production AMBRX, INC. (US) 2026-03-17 — — US claimed
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates SUTRO BIOPHARMA, INC. (US) 2026-02-03 — — US claimed
US-20250325632-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES Synthorx, Inc. (US) 2025-10-23 — — US claimed
US-20250327074-A1 THE RARE CODON RECODING PLATFORM FOR NONCANONICAL AMINO ACIDS INCORPORATION IN MAMMALIAN CELLS SHAOXING INSTITUTE, ZHEJIANG UNIVERSITY (CN) 2025-10-23 — — US claimed
US-20250325633-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES Synthorx, Inc. (US) 2025-10-23 — — US claimed
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. 2025-10-02 — — US claimed
US-12427201-B2 Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates SUTRO BIOPHARMA, INC. (US) 2025-09-30 — — US claimed
EP-3788149-B1 A METHOD FOR OPTIMIZING ANTIBODY EXPRESSION AMBRX INC (US) 2025-08-27 — — EP claimed
US-12377131-B2 Cytokine conjugates for the treatment of autoimmune diseases Synthorx, Inc. (US) 2025-08-05 — — US claimed
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2025-07-24 — — US claimed
US-20070178448-A1 Selective posttranslational modification of phage-displayed polypeptides THE SCRIPPS RESEARCH INSTITUTE (US) 2007-08-02 — — US claimed
US-20070154952-A1 Expanding the eukaryotic genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2007-07-05 — — US claimed
US-20060246509-A1 protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors THE SCRIPPS RESEARCH INSTITUTE 2006-11-02 — — US claimed
US-20060073507-A1 Orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases incorporate para-propargyloxyphenylalanine into proteins produced in E. coli THE SCRIPPS RESEARCH INSTITUTE (US) 2006-04-06 — — US claimed
EP-1636340-A2 UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS The Scripps Research Institute (US) 2006-03-22 — — EP claimed
EP-1613735-A2 EXPANDING THE EUKARYOTIC GENETIC CODE The Scripps Research Institute (US) 2006-01-11 — — EP claimed
WO-2005003294-A2 UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2005-01-13 — — WO claimed
US-20050009049-A1 Expanding the eukaryotic genetic code THE SCRIPPS RESEARCH INSTITUTE (US) 2005-01-13 — — US claimed
US-20040265952-A1 protein containing a modified amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug that carries an alkynyl or azido group; translation biochemistry in eukaryotic cells; gene expression inhibitors THE SCRIPPS RESEARCH INSTITUTE (US) 2004-12-30 — — US claimed
WO-2004094593-A2 EXPANDING THE EUKARYOTIC GENETIC CODE THE SCRIPPS RESEARCH INSTITUTE (US) 2004-11-04 — — WO claimed
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