Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 7/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929153 | 0.86 | MAPT (0.37) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL18202638 | 0.82 | MAPT (0.46) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL25768555 | 0.81 | MAPT (0.44) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL4376366 | 0.81 | MAPT (0.41) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL29428465 | 0.80 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL1615138 | 0.80 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL1614172 | 0.80 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL108341 | 0.80 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL29353913 | 0.80 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL29785792 | 0.80 | MAPT (0.43) | MAPTCYP1A2CYP3A4CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7740482-B2 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | BLUESTAR SILICONES FRANCE (FR) | 2010-06-22 | — | — | US | claimed |
| EP-1745083-B1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | BLUESTAR SILICONES FRANCE (FR) | 2009-12-16 | — | — | EP | claimed |
| WO-2009126515-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-10-15 | — | — | WO | claimed |
| US-20080287562-A1 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | RHODIA CHIMIE (FR) | 2008-11-20 | — | — | US | claimed |
| EP-1745083-A1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | Rhodia Chimie (FR) | 2007-01-24 | — | — | EP | claimed |
| WO-2005121200-A1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | RHODIA CHIMIE (FR) | 2005-12-22 | — | — | WO | claimed |
| US-20050261390-A1 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | RHODIA CHIMIE (FR) | 2005-11-24 | — | — | US | claimed |
| US-8916624-B2 | Dental compositions crosslinkable/polymerizable by cationic process | BLUESTAR SILICONES FRANCE SAS (FR) | 2014-12-23 | — | — | US | disclosed |
| US-20110189632-A1 | DENTAL COMPOSITIONS CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS | BLUESTAR SILICONES FRANCE (FR) | 2011-08-04 | — | — | US | disclosed |
| US-7740482-B2 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | BLUESTAR SILICONES FRANCE (FR) | 2010-06-22 | — | — | US | disclosed |
| EP-1745083-B1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | BLUESTAR SILICONES FRANCE (FR) | 2009-12-16 | — | — | EP | disclosed |
| EP-2043588-B1 | DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS | BLUESTAR SILICONES FRANCE (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-20080287562-A1 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | RHODIA CHIMIE (FR) | 2008-11-20 | — | — | US | disclosed |
| EP-1745083-A1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | Rhodia Chimie (FR) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005121200-A1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | RHODIA CHIMIE (FR) | 2005-12-22 | — | — | WO | disclosed |
| US-20050261390-A1 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | RHODIA CHIMIE (FR) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287562-A1 | Stable cationically crosslinkable/polymerizable dental composition with a high filler content | RFC1, RFC2, HNRNPC | MAPT 3057/4885CYP1A2 3318/4885CYP3A4 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.