Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202638 | 0.85 | MAPT (0.46) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL25768555 | 0.84 | MAPT (0.44) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL1614172 | 0.83 | MAPT (0.43) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL1615138 | 0.83 | MAPT (0.43) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL108341 | 0.83 | MAPT (0.43) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL29428465 | 0.83 | MAPT (0.43) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL29785792 | 0.83 | MAPT (0.43) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL29353913 | 0.83 | MAPT (0.43) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL2296048 | 0.81 | MAPT (0.39) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 | |
| SCHEMBL23226923 | 0.80 | CNR1 (0.44) | MAPTCYP1A2CYP3A4RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745083-B1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | BLUESTAR SILICONES FRANCE (FR) | 2009-12-16 | — | — | EP | claimed |
| EP-1745083-B1 | HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION | BLUESTAR SILICONES FRANCE (FR) | 2009-12-16 | — | — | EP | disclosed |
| EP-2043588-B1 | DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS | BLUESTAR SILICONES FRANCE (FR) | 2009-11-18 | — | — | EP | disclosed |