Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 6/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141413 | 0.83 | FFAR1 (0.52) | FFAR1DGAT1GSK3AGSK3BUSP30 | |
| SCHEMBL22334710 | 0.82 | FFAR1 (0.42) | FFAR1DGAT1LPLLIPGGSK3A | |
| SCHEMBL17165884 | 0.81 | FFAR1 (0.45) | FFAR1DGAT1LPLLIPGGSK3A | |
| SCHEMBL1650157 | 0.80 | FFAR1 (0.50) | FFAR1DGAT1LPLLIPGGSK3A | |
| SCHEMBL20733996 | 0.79 | FFAR1 (0.45) | FFAR1DGAT1GSK3AGSK3BUSP30 | |
| SCHEMBL1269464 | 0.76 | FFAR1 (0.47) | FFAR1DGAT1USP30PRMT5WDR77 | |
| SCHEMBL19341509 | 0.76 | FFAR1 (0.44) | FFAR1DGAT1USP30PRMT5WDR77 | |
| SCHEMBL19672040 | 0.76 | FFAR1 (0.44) | FFAR1DGAT1USP30PRMT5WDR77 | |
| SCHEMBL6644374 | 0.75 | FFAR1 (0.43) | FFAR1DGAT1LPLLIPGUSP30 | |
| SCHEMBL18202880 | 0.74 | FFAR1 (0.43) | FFAR1DGAT1USP30PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026451-A1 | COMPOUNDS AND METHOD FOR TREATING CYTOKINE RELEASE SYNDROME | RIGEL PHARMACEUTICALS, INC. (US) | 2021-02-11 | — | — | WO | disclosed |